Pharmaceutical Insights
Navigate pharmaceutical trends with our insights on targets, institutional pipelines, clinical advances, and new drugs.
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Recent blog posts
Exploring Riluzole's R&D successes and its clinical results at the 2024 ASCO_GI
Exploring Riluzole's R&D successes and its clinical results at the 2024 ASCO_GI
19 February 2024
Colorectal cancer (CRC) ranks second in US cancer deaths. 5-fluorouracil (5-FU) therapies with targeted drugs are the go-to for advanced cases.
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In a Phase 2b trial, the oral peptide JNJ-2113 showed promise for moderate to severe psoriasis
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In a Phase 2b trial, the oral peptide JNJ-2113 showed promise for moderate to severe psoriasis
19 February 2024
In a Phase 2b clinical trial, the experimental oral peptide known as JNJ-2113 has shown encouraging outcomes for patients with moderate to severe psoriasis.
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Navigating Health Information: How to Use Synapse to Search for Oxytocin
Drug Insights
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Navigating Health Information: How to Use Synapse to Search for Oxytocin
19 February 2024
Oxytocin, an OXTR agonist marketed under the trade name OXYTOCIN®, is a medication that has been lauded for its clinical efficacy in the field of obstetrics and gynecology.
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REGENXBIO Hits Key Goal in RGX-121 Study for MPS II
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REGENXBIO Hits Key Goal in RGX-121 Study for MPS II
19 February 2024
REGENXBIO Confirms Major Milestone Reached in Crucial Study of RGX-121 as Therapy for MPS II, Successfully Hitting Primary Goal.
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Pegfilgrastim: A Quick Look at Its R&D Progress and Clinical Results from the 2024 ASCO_GI
Pegfilgrastim: A Quick Look at Its R&D Progress and Clinical Results from the 2024 ASCO_GI
19 February 2024
The initial FOLFIRINOX protocol for PDAC carries a high FN risk; pegfilgrastim mitigates this, but optimal duration is uncertain.
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Initial Human Participant Receives ZMA001 in Medical Study Targeting PAH Therapy
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Initial Human Participant Receives ZMA001 in Medical Study Targeting PAH Therapy
19 February 2024
Zymedi has begun first human trials of ZMA001, a novel monoclonal antibody for treating Pulmonary Arterial Hypertension.
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Optimize Your Synapse Experience: A Step-by-Step Guide to Searching Dopamine
Drug Insights
2 min read
Optimize Your Synapse Experience: A Step-by-Step Guide to Searching Dopamine
19 February 2024
Dopamine hydrochloride, first approved in the USA on February 25, 1974, is a medication developed and marketed by Hospira.
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US FDA & Australian Health Authorities Approve ETX101, Encoded Therapeutics' Potential Genetic Treatment for Dravet Syndrome
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US FDA & Australian Health Authorities Approve ETX101, Encoded Therapeutics' Potential Genetic Treatment for Dravet Syndrome
18 February 2024
Encoded Therapeutics Reveals Approval from US FDA for IND Application and Consent from Australian Health Authorities for ETX101, a Genetic Treatment Prospect for Dravet Syndrome.
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An analysis of LY-3537982's R&D progress and its clinical results presented at the 2024 ASCO_GI Annual Meeting
An analysis of LY-3537982's R&D progress and its clinical results presented at the 2024 ASCO_GI Annual Meeting
18 February 2024
LY3537982: A Potent Oral Inhibitor for KRAS G12C Mutation in GI Tumors - Results from 2024 ASCO-GI LOXO-RAS-20001 Phase 1 Study.
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Scholar Rock Unveils Initial Lab Results Indicating Advantages of SRK-439 in Supporting Weight Reduction
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Scholar Rock Unveils Initial Lab Results Indicating Advantages of SRK-439 in Supporting Weight Reduction
18 February 2024
Scholar Rock's Study Reveals SRK-439's Potential Influence on Muscle Mass and Metabolic Health in Weight Loss Efforts.
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The Synapse User's Toolkit: Tips for Searching Naltrexone
Drug Insights
2 min read
The Synapse User's Toolkit: Tips for Searching Naltrexone
18 February 2024
Naltrexone, an opioid antagonist, has been utilized for treating addiction to both drugs and alcohol.
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Orchard Therapeutics Begins OTL-203 Study for Hurler's Syndrome in MPS-I
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Orchard Therapeutics Begins OTL-203 Study for Hurler's Syndrome in MPS-I
18 February 2024
Orchard Therapeutics Reveals Enrollment of Initial Participant in Key Study of OTL-203 Targeting Hurler's Syndrome in MPS-I.
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